Sunday, February 24, 2008

Autism symptoms reversed in Fragile X mice

The researchers, based at MIT's Picower Institute for Learning and Memory, targeted an enzyme called PAK which affects the number, size and shape of connection between brain cells.

They found that inhibiting the enzyme stopped mice with Fragile X Syndrome behaving in erratic ways.

Prior to treatment they showed signs of hyperactivity, purposeless and repetitive movements.

Further analysis showed that not only were structural abnormalities in connections between brain cells righted, proper electrical communication was restored between the cells.

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