Topiramate, an anti-convulsant, helps alcoholics quit

By the end of the study, those receiving the drug reported drinking heavily on just 20% of days. They also averaged only 3.5 drinks per day, and managed to stay completely sober more than half the time.
The control group also improved, but significantly less. They drank heavily on more than 40% of days, consumed six drinks per day, and abstained from drinking about a third of the time.
Topiramate works by blocking the release of the neurotransmitter dopamine, which reinforces the pleasurable feelings that alcoholics get when they drink.